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Jpn. J. Appl. Phys. 45 (2006) pp. 5254-5262  |Previous Article| |Next Article|  |Table of Contents|
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Phase Tomography by X-ray Talbot Interferometry for Biological Imaging

Atsushi Momose, Wataru Yashiro, Yoshihiro Takeda1, Yoshio Suzuki2 and Tadashi Hattori3

Department of Advanced Materials Science, School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan
1Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan
2Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo, Hyogo 679-5198, Japan
3Laboratory of Advanced Science and Technology for Industry, University of Hyogo, 3-1-2 Kouto, Kamigori, Hyogo 678-1205, Japan

(Received December 13, 2005; accepted March 5, 2006; published online June 8, 2006)

The X-ray phase tomography of biological samples is reported, which is based on X-ray Talbot interferometry. Its imaging principle is described in detail, and imaging results obtained for a cancerous rabbit liver and a mouse tail with synchrotron radiation are presented. Because an amplitude grating is needed to construct an X-ray Talbot interferometer, a high-aspect-ratio grating pattern was fabricated by X-ray lithography and gold electroplating. X-ray Talbot interferometry has an advantage that it functions with polychromatic cone-beam X-rays. Finally, the compatibility with a compact X-ray source is discussed.

URL: http://jjap.jsap.jp/link?JJAP/45/5254/
DOI: 10.1143/JJAP.45.5254


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